Cargando…
Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance
Both medullary thymic epithelial cells (mTEC) and dendritic cells (DC) present tissue-restricted antigens (TRA) to thymocytes to induce central tolerance, but the relative contributions of these antigen-presenting cell (APC) subsets remain unresolved. Here we developed a two-photon microscopy approa...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525199/ https://www.ncbi.nlm.nih.gov/pubmed/31101805 http://dx.doi.org/10.1038/s41467-019-09727-4 |