Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance

Both medullary thymic epithelial cells (mTEC) and dendritic cells (DC) present tissue-restricted antigens (TRA) to thymocytes to induce central tolerance, but the relative contributions of these antigen-presenting cell (APC) subsets remain unresolved. Here we developed a two-photon microscopy approa...

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Detalles Bibliográficos
Autores principales: Lancaster, J. N., Thyagarajan, H. M., Srinivasan, J., Li, Y., Hu, Z., Ehrlich, L. I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525199/
https://www.ncbi.nlm.nih.gov/pubmed/31101805
http://dx.doi.org/10.1038/s41467-019-09727-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525199/
https://www.ncbi.nlm.nih.gov/pubmed/31101805
http://dx.doi.org/10.1038/s41467-019-09727-4

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