System x(c)(−) in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness

Post-septic neurological and psychiatric illness (PSNPI) including dementia and depression may be observed after sepsis. However, the etiology of PSNPI and therapeutic treatment of PSNPI are unclear. We show that glutamate produced from microglia through the activity of system x(c)(−) plays a role i...

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Detalles Bibliográficos
Autores principales: Kitagawa, Yoshinori, Nakaso, Kazuhiro, Horikoshi, Yosuke, Morimoto, Masaki, Omotani, Takuma, Otsuki, Akihiro, Inagaki, Yoshimi, Sato, Hideyo, Matsura, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525204/
https://www.ncbi.nlm.nih.gov/pubmed/31101857
http://dx.doi.org/10.1038/s41598-019-44006-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525204/
https://www.ncbi.nlm.nih.gov/pubmed/31101857
http://dx.doi.org/10.1038/s41598-019-44006-8

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