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System x(c)(−) in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness
Post-septic neurological and psychiatric illness (PSNPI) including dementia and depression may be observed after sepsis. However, the etiology of PSNPI and therapeutic treatment of PSNPI are unclear. We show that glutamate produced from microglia through the activity of system x(c)(−) plays a role i...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525204/ https://www.ncbi.nlm.nih.gov/pubmed/31101857 http://dx.doi.org/10.1038/s41598-019-44006-8 |