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Optimizing the dynamics of protein expression

Heterologously expressed genes require adaptation to the host organism to ensure adequate levels of protein synthesis, which is typically approached by replacing codons by the target organism’s preferred codons. In view of frequently encountered suboptimal outcomes we introduce the codon-specific el...

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Detalles Bibliográficos
Autores principales: Trösemeier, Jan-Hendrik, Rudorf, Sophia, Loessner, Holger, Hofner, Benjamin, Reuter, Andreas, Schulenborg, Thomas, Koch, Ina, Bekeredjian-Ding, Isabelle, Lipowsky, Reinhard, Kamp, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525252/
https://www.ncbi.nlm.nih.gov/pubmed/31101858
http://dx.doi.org/10.1038/s41598-019-43857-5