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Optimizing the dynamics of protein expression
Heterologously expressed genes require adaptation to the host organism to ensure adequate levels of protein synthesis, which is typically approached by replacing codons by the target organism’s preferred codons. In view of frequently encountered suboptimal outcomes we introduce the codon-specific el...
Autores principales: | Trösemeier, Jan-Hendrik, Rudorf, Sophia, Loessner, Holger, Hofner, Benjamin, Reuter, Andreas, Schulenborg, Thomas, Koch, Ina, Bekeredjian-Ding, Isabelle, Lipowsky, Reinhard, Kamp, Christel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525252/ https://www.ncbi.nlm.nih.gov/pubmed/31101858 http://dx.doi.org/10.1038/s41598-019-43857-5 |
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