Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures

Changes in bulk transcriptional profiles of heterogeneous samples often reflect changes in proportions of individual cell types. Several robust techniques have been developed to dissect the composition of such mixed samples given transcriptional signatures of the pure components or their proportions...

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Detalles Bibliográficos
Autores principales: Zaitsev, Konstantin, Bambouskova, Monika, Swain, Amanda, Artyomov, Maxim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525259/
https://www.ncbi.nlm.nih.gov/pubmed/31101809
http://dx.doi.org/10.1038/s41467-019-09990-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525259/
https://www.ncbi.nlm.nih.gov/pubmed/31101809
http://dx.doi.org/10.1038/s41467-019-09990-5

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