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Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures
Changes in bulk transcriptional profiles of heterogeneous samples often reflect changes in proportions of individual cell types. Several robust techniques have been developed to dissect the composition of such mixed samples given transcriptional signatures of the pure components or their proportions...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525259/ https://www.ncbi.nlm.nih.gov/pubmed/31101809 http://dx.doi.org/10.1038/s41467-019-09990-5 |