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Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect

Apart from osteogenesis, neovascularization of the defect area is an important determinant for successful bone healing. Accordingly, several studies have employed the combined delivery of VEGFA and BMP2 for bone regeneration. Nevertheless, the outcomes of these studies are highly variable. The aim o...

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Detalles Bibliográficos
Autores principales: Sharma, Sunita, Xue, Ying, Xing, Zhe, Yassin, Mohammed A., Sun, Yang, Lorens, James B., Finne-Wistrand, Anna, Sapkota, Dipak, Mustafa, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525280/
https://www.ncbi.nlm.nih.gov/pubmed/31193299
http://dx.doi.org/10.1016/j.bonr.2019.100205