Significance of sphingosine kinase 1 expression in feline mammary tumors

BACKGROUND: Sphingosine kinase 1 (SPHK1) is an enzyme that converts pro-apoptotic ceramide and sphingosine into anti-apoptotic sphingosine-1-phosphate. There is growing evidence that SPHK1 activation promotes oncogenic transformation, tumor growth, chemotherapy resistance, and metastatic spread. Hig...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Chih, Chuang, Hsiao-Li, Yin, Ji-Hang, Liao, Jiunn-Wang, Chen, Ter-Hsin, Wang, Yu-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525354/
https://www.ncbi.nlm.nih.gov/pubmed/31101115
http://dx.doi.org/10.1186/s12917-019-1883-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525354/
https://www.ncbi.nlm.nih.gov/pubmed/31101115
http://dx.doi.org/10.1186/s12917-019-1883-z

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