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Linear time minimum segmentation enables scalable founder reconstruction

BACKGROUND:  We study a preprocessing routine relevant in pan-genomic analyses: consider a set of aligned haplotype sequences of complete human chromosomes. Due to the enormous size of such data, one would like to represent this input set with a few founder sequences that retain as well as possible...

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Detalles Bibliográficos
Autores principales: Norri, Tuukka, Cazaux, Bastien, Kosolobov, Dmitry, Mäkinen, Veli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525415/
https://www.ncbi.nlm.nih.gov/pubmed/31131017
http://dx.doi.org/10.1186/s13015-019-0147-6