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Accuracy of analysis of cfDNA for detection of single nucleotide variants and copy number variants in breast cancer

BACKGROUND: Gene variants are dependable and sensitive biomarkers for target-specific therapies in breast cancer (BC). However, detection of mutations within tissues has many limitations. Plasma circulating free DNA (cfDNA) has been reported in many studies as an alternative tool for detection of mu...

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Detalles Bibliográficos
Autores principales: Yang, Xin, Zhang, Kuo, Zhang, Caiji, Peng, Rongxue, Sun, Chengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525451/
https://www.ncbi.nlm.nih.gov/pubmed/31101027
http://dx.doi.org/10.1186/s12885-019-5698-x