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Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis

Regional differences in neurons, astrocytes, oligodendrocytes, and microglia exist in the brain during health, and regional differences in the transcriptome may occur for each cell type during neurodegeneration. Multiple sclerosis (MS) is multifocal, and regional differences in the astrocyte transcr...

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Detalles Bibliográficos
Autores principales: Voskuhl, Rhonda R., Itoh, Noriko, Tassoni, Alessia, Matsukawa, Macy Akiyo, Ren, Emily, Tse, Vincent, Jang, Ellis, Suen, Timothy Takazo, Itoh, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525478/
https://www.ncbi.nlm.nih.gov/pubmed/31040210
http://dx.doi.org/10.1073/pnas.1821306116