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Defining the core essential genome of Pseudomonas aeruginosa

Genomics offered the promise of transforming antibiotic discovery by revealing many new essential genes as good targets, but the results fell short of the promise. While numerous factors contributed to the disappointing yield, one factor was that essential genes for a bacterial species were often de...

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Detalles Bibliográficos
Autores principales: Poulsen, Bradley E., Yang, Rui, Clatworthy, Anne E., White, Tiantian, Osmulski, Sarah J., Li, Li, Penaranda, Cristina, Lander, Eric S., Shoresh, Noam, Hung, Deborah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525520/
https://www.ncbi.nlm.nih.gov/pubmed/31036669
http://dx.doi.org/10.1073/pnas.1900570116