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Defining the core essential genome of Pseudomonas aeruginosa
Genomics offered the promise of transforming antibiotic discovery by revealing many new essential genes as good targets, but the results fell short of the promise. While numerous factors contributed to the disappointing yield, one factor was that essential genes for a bacterial species were often de...
Autores principales: | Poulsen, Bradley E., Yang, Rui, Clatworthy, Anne E., White, Tiantian, Osmulski, Sarah J., Li, Li, Penaranda, Cristina, Lander, Eric S., Shoresh, Noam, Hung, Deborah T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525520/ https://www.ncbi.nlm.nih.gov/pubmed/31036669 http://dx.doi.org/10.1073/pnas.1900570116 |
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