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Mesenchymal Stem Cells Derived and Cultured from Glioblastoma Multiforme Increase Tregs, Downregulate Th17, and Induce the Tolerogenic Phenotype of Monocyte-Derived Cells

Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics—first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their in vit...

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Detalles Bibliográficos
Autores principales: Tumangelova-Yuzeir, Kalina, Naydenov, Emanuil, Ivanova-Todorova, Ekaterina, Krasimirova, Ekaterina, Vasilev, Georgi, Nachev, Sevdalin, Kyurkchiev, Dobroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525812/
https://www.ncbi.nlm.nih.gov/pubmed/31191680
http://dx.doi.org/10.1155/2019/6904638