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iTRAQ-Based Protein Profiling in CUMS Rats Provides Insights into Hippocampal Ribosome Lesion and Ras Protein Changes Underlying Synaptic Plasticity in Depression

Hippocampal atrophy is one of the key changes in the brain implicated in the biology of depression. However, the precise molecular mechanism remains poorly understood due to a lack of biomarkers. In this research, we used behavioral experiments to evaluate anxiety and anhedonia levels in depressed r...

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Detalles Bibliográficos
Autores principales: Zhang, Jialing, Zhang, Zhinan, Zhang, Jiping, Zhong, Zheng, Yao, Zengyu, Qu, Shanshan, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525853/
https://www.ncbi.nlm.nih.gov/pubmed/31191638
http://dx.doi.org/10.1155/2019/7492306