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Traditional Herbal Formula Taeeumjowi-Tang (TJ001) Inhibits p53-Mutant Prostate Cancer Cells Growth by Activating AMPK-Dependent Pathway

Dysregulated lipid metabolism is a prominent feature of prostate cancers (PCas); several enzymes involved in lipid accumulation are highly expressed. Here, we elucidated efficacy of TJ001, a traditional herbal decoction, in inhibiting de novo lipogenesis. TJ001 had significant cytotoxicity against D...

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Detalles Bibliográficos
Autores principales: Kang, Sooyeon, Kim, Hyo In, Choi, Yu-Jeong, Lee, Seul Ki, Kim, Ji Hye, Cheon, Chunhoo, Ko, Seong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525874/
https://www.ncbi.nlm.nih.gov/pubmed/31191706
http://dx.doi.org/10.1155/2019/2460353