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Intradiscal Injection of Induced Pluripotent Stem Cell-Derived Nucleus Pulposus-Like Cell-Seeded Polymeric Microspheres Promotes Rat Disc Regeneration

BACKGROUND: Cell replacement therapy is an attractive alternative for treating degenerated intervertebral discs (IVDs), which are related to the reduction of nucleus pulposus-like cells (NP-lCs) and the loss of the extracellular matrix. Induced pluripotent stem cells (iPSCs) which resemble embryonic...

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Detalles Bibliográficos
Autores principales: Xia, Kaishun, Zhu, Jian, Hua, Jianming, Gong, Zhe, Yu, Chao, Zhou, Xiaopeng, Wang, Jingkai, Huang, Xianpeng, Yu, Wei, Li, Liming, Gao, Jianqing, Chen, Qixin, Li, Fangcai, Liang, Chengzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525958/
https://www.ncbi.nlm.nih.gov/pubmed/31191679
http://dx.doi.org/10.1155/2019/6806540