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miR-381 Attenuates Peripheral Neuropathic Phenotype Caused by Overexpression of PMP22

Charcot-Marie Tooth disease type 1A (CMT1A), the major type of CMT, is caused by duplication of peripheral myelin protein 22 (PMP22) gene whose overexpression causes structural and functional abnormalities in myelination. We investigated whether miRNA-mediated regulation of PMP22 expression could re...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Su, Kwak, Geon, Kim, Hye Jin, Park, Hwan-Tae, Choi, Byung-Ok, Hong, Young Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526106/
https://www.ncbi.nlm.nih.gov/pubmed/31138995
http://dx.doi.org/10.5607/en.2019.28.2.279