Rab GTPases as Physiological Substrates of LRRK2 Kinase

LRRK2 (Leucine-Rich Repeat Kinase 2) is a gene whose specific mutations cause Parkinson's disease (PD), the most common neurodegenerative movement disorder. LRRK2 harbors GTPase and kinase activities, two enzyme activities that play critical roles in the regulation of cellular signal transducti...

Descripción completa

Detalles Bibliográficos
Autores principales: Seol, Wongi, Nam, Daleum, Son, Ilhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526114/
https://www.ncbi.nlm.nih.gov/pubmed/31138985
http://dx.doi.org/10.5607/en.2019.28.2.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526114/
https://www.ncbi.nlm.nih.gov/pubmed/31138985
http://dx.doi.org/10.5607/en.2019.28.2.134

Ejemplares similares