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C3a Receptor Inhibition Protects Brain Endothelial Cells Against Oxygen-glucose Deprivation/Reperfusion

The complement cascade is a central component of innate immunity which plays a critical role in brain inflammation. Complement C3a receptor (C3aR) is a key mediator of post-ischemic cerebral injury, and pharmacological antagonism of the C3a receptor is neuroprotective in stroke. Cerebral ischemia in...

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Detalles Bibliográficos
Autores principales: Ahmad, Saif, Kindelin, Adam, Khan, Shah Alam, Ahmed, Maaz, Hoda, Md Nasrul, Bhatia, Kanchan, Ducruet, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526115/
https://www.ncbi.nlm.nih.gov/pubmed/31138990
http://dx.doi.org/10.5607/en.2019.28.2.216