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C3a Receptor Inhibition Protects Brain Endothelial Cells Against Oxygen-glucose Deprivation/Reperfusion
The complement cascade is a central component of innate immunity which plays a critical role in brain inflammation. Complement C3a receptor (C3aR) is a key mediator of post-ischemic cerebral injury, and pharmacological antagonism of the C3a receptor is neuroprotective in stroke. Cerebral ischemia in...
Autores principales: | Ahmad, Saif, Kindelin, Adam, Khan, Shah Alam, Ahmed, Maaz, Hoda, Md Nasrul, Bhatia, Kanchan, Ducruet, Andrew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Brain and Neural Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526115/ https://www.ncbi.nlm.nih.gov/pubmed/31138990 http://dx.doi.org/10.5607/en.2019.28.2.216 |
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