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Proposing a validation scheme for (13)C metabolite tracer studies in high-resolution mass spectrometry
(13)C metabolite tracer and metabolic flux analyses require upfront experimental planning and validation tools. Here, we present a validation scheme including a comparison of different LC methods that allow for customization of analytical strategies for tracer studies with regard to the targeted met...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526147/ https://www.ncbi.nlm.nih.gov/pubmed/30972471 http://dx.doi.org/10.1007/s00216-019-01773-7 |