HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells

HSP60 is a major mitochondrial chaperone for maintaining mitochondrial proteostasis. Our previous studies showed that HSP60 was significantly downregulated in clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer characterized by the classic Warburg effect. Here, we analyzed...

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Detalles Bibliográficos
Autores principales: Teng, Ruifang, Liu, Zongyuan, Tang, Haiping, Zhang, Wenhao, Chen, Yuling, Xu, Renhua, Chen, Liang, Song, Jiangping, Liu, Xiaohui, Deng, Haiteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526248/
https://www.ncbi.nlm.nih.gov/pubmed/31112866
http://dx.doi.org/10.1016/j.redox.2019.101218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526248/
https://www.ncbi.nlm.nih.gov/pubmed/31112866
http://dx.doi.org/10.1016/j.redox.2019.101218

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