Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

We leveraged a human gut-on-a-chip (Gut Chip) microdevice that enables independent control of fluid flow and mechanical deformations to explore how physical cues and morphogen gradients influence intestinal morphogenesis. Both human intestinal Caco-2 and intestinal organoid-derived primary epithelia...

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Detalles Bibliográficos
Autores principales: Shin, Woojung, Hinojosa, Christopher D., Ingber, Donald E., Kim, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526295/
https://www.ncbi.nlm.nih.gov/pubmed/31108394
http://dx.doi.org/10.1016/j.isci.2019.04.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526295/
https://www.ncbi.nlm.nih.gov/pubmed/31108394
http://dx.doi.org/10.1016/j.isci.2019.04.037

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