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SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism()

SIRT3 is a major mitochondrial deacetylase, which regulates various metabolic pathways by deacetylation; however, the effect of SIRT3 on proline metabolism is not reported. Pyrroline-5-carboxylate reductase 1 (PYCR1) participates in proline synthesis process by catalyzing the reduction of P5C to pro...

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Detalles Bibliográficos
Autores principales: Chen, Shuaiyi, Yang, Xin, Yu, Miao, Wang, Zhe, Liu, Boya, Liu, Minghui, Liu, Lu, Ren, Mengmeng, Qi, Hao, Zou, Junhua, Vucenik, Ivana, Zhu, Wei-Guo, Luo, Jianyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526305/
https://www.ncbi.nlm.nih.gov/pubmed/31108370
http://dx.doi.org/10.1016/j.neo.2019.04.008