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IL-1 beta-mediated macrophage-hepatocyte crosstalk upregulates hepcidin under physiological low oxygen levels

In mammals, the iron masterswitch hepcidin efficiently controls iron recycling by the macrophage-liver axis but the exact interplay between macrophages and hepatocytes remains poorly understood. We here study hepcidin response during macrophage differentiation as well as the macrophage-hepatocyte cr...

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Detalles Bibliográficos
Autores principales: Silva, Inês, Peccerella, Teresa, Mueller, Sebastian, Rausch, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526398/
https://www.ncbi.nlm.nih.gov/pubmed/31108461
http://dx.doi.org/10.1016/j.redox.2019.101209