Predictable Peptide Conjugation Ratios by Activation of Proteins with Succinimidyl Iodoacetate (SIA)

The small heterobifunctional linker succinimidyl iodoacetate (SIA) was examined for the preparation of peptide–protein bioconjugates with predicable conjugation ratios. For many conjugation protocols, the protein is either treated with a reductant to cleave disulfide bonds or is reacted with thiolat...

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Detalles Bibliográficos
Autores principales: Abbas, Ioana M., Schwaar, Timm, Bienwald, Frank, Weller, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526413/
https://www.ncbi.nlm.nih.gov/pubmed/31164550
http://dx.doi.org/10.3390/mps1010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526413/
https://www.ncbi.nlm.nih.gov/pubmed/31164550
http://dx.doi.org/10.3390/mps1010002

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