Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

Mitochondrial cholesterol accumulation is a hallmark of alcoholic and non-alcoholic fatty liver diseases and impairs the function of specific solute carriers through changes in membrane physical properties. However, its impact on mitochondrial respiration and organization of respiratory supercomplex...

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Detalles Bibliográficos
Autores principales: Solsona-Vilarrasa, Estel, Fucho, Raquel, Torres, Sandra, Nuñez, Susana, Nuño-Lámbarri, Natalia, Enrich, Carlos, García-Ruiz, Carmen, Fernández-Checa, José C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526464/
https://www.ncbi.nlm.nih.gov/pubmed/31108462
http://dx.doi.org/10.1016/j.redox.2019.101214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526464/
https://www.ncbi.nlm.nih.gov/pubmed/31108462
http://dx.doi.org/10.1016/j.redox.2019.101214

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