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Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent

Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells and the release of proinflammatory cytokines. O...

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Detalles Bibliográficos
Autores principales: Idosa, Berhane Asfaw, Kelly, Anne, Jacobsson, Susanne, Demirel, Isak, Fredlund, Hans, Särndahl, Eva, Persson, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526529/
https://www.ncbi.nlm.nih.gov/pubmed/31198794
http://dx.doi.org/10.1155/2019/6193186