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Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent
Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells and the release of proinflammatory cytokines. O...
Autores principales: | Idosa, Berhane Asfaw, Kelly, Anne, Jacobsson, Susanne, Demirel, Isak, Fredlund, Hans, Särndahl, Eva, Persson, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526529/ https://www.ncbi.nlm.nih.gov/pubmed/31198794 http://dx.doi.org/10.1155/2019/6193186 |
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