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A Bacillus-based Coxsackie virus A16 mucosal vaccine induces strong neutralizing antibody responses
The purpose of this study was to construct a Coxsackie virus A16 (CA16) mucosal vaccine and evaluate its ability to induce immune response. VP1 gene of CA16 was inserted into the genome of Bacillus subtilis via recombination and displayed on the surface of the spores. This Bacillus-based vaccine was...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Polish Society of Experimental and Clinical Immunology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526588/ https://www.ncbi.nlm.nih.gov/pubmed/31114430 http://dx.doi.org/10.5114/ceji.2019.84009 |