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A Bacillus-based Coxsackie virus A16 mucosal vaccine induces strong neutralizing antibody responses

The purpose of this study was to construct a Coxsackie virus A16 (CA16) mucosal vaccine and evaluate its ability to induce immune response. VP1 gene of CA16 was inserted into the genome of Bacillus subtilis via recombination and displayed on the surface of the spores. This Bacillus-based vaccine was...

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Detalles Bibliográficos
Autores principales: Cao, Yin-Guang, Hao, Yu, Wang, Lexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526588/
https://www.ncbi.nlm.nih.gov/pubmed/31114430
http://dx.doi.org/10.5114/ceji.2019.84009