Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats

Maprotiline, a tetracyclic antidepressant, is used for the management of mental disorders and various types of chronic pain. In our previous work, we found the inhibitory effect of maprotiline on inflammatory mediator’s expression like tumor necrosis factor α (TNF-α and interleukin 1β (IL-1β. As par...

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Detalles Bibliográficos
Autores principales: Rafiee, Laleh, Hajhashemi, Valiollah, Javanmard, Shaghayegh Haghjooy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2019
Materias:
Experimental Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526590/
https://www.ncbi.nlm.nih.gov/pubmed/31114432
http://dx.doi.org/10.5114/ceji.2019.84011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526590/
https://www.ncbi.nlm.nih.gov/pubmed/31114432
http://dx.doi.org/10.5114/ceji.2019.84011

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