Metformin‐induced autophagy and irisin improves INS‐1 cell function and survival in high‐glucose environment via AMPK/SIRT1/PGC‐1α signal pathway

In order to explore the protective function of metformin on pancreatic β cells to alleviate insulin resistance and underlying mechanisms, INS‐1 cells were cultured into normal control (N), high glucose (H), high glucose and metformin (H + Met), high glucose and chloroquine (H + CQ), and high glucose...

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Detalles Bibliográficos
Autores principales: Li, Qingxue, Jia, Shaohui, Xu, Lei, Li, Biao, Chen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526663/
https://www.ncbi.nlm.nih.gov/pubmed/31139382
http://dx.doi.org/10.1002/fsn3.1006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526663/
https://www.ncbi.nlm.nih.gov/pubmed/31139382
http://dx.doi.org/10.1002/fsn3.1006

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