Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a

Rab GTPases are compartment-specific molecular switches that regulate intracellular vesicular transport in eukaryotes. GDP/GTP exchange factors (GEFs) control Rab activation, and current models propose that localised and regulated GEF activity is important in targeting Rabs to specific membranes. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanzà, Paolo, Evans, Richard D., Briggs, Deborah A., Cantero, Marta, Montoliu, Lluis, Patel, Shyamal, Sviderskaya, Elena V., Itzen, Aymelt, Figueiredo, Ana C., Seabra, Miguel C., Hume, Alistair N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526710/
https://www.ncbi.nlm.nih.gov/pubmed/30898842
http://dx.doi.org/10.1242/jcs.212035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526710/
https://www.ncbi.nlm.nih.gov/pubmed/30898842
http://dx.doi.org/10.1242/jcs.212035

Ejemplares similares