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Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells

Macroautophagy/autophagy is a cellular degradation pathway that delivers cytoplasmic material to lysosomes via double-membrane organelles called autophagosomes. Lipidation of ubiquitin-like LC3/GABARAP proteins on the autophagosome membrane is important for autophagy. The cysteine protease ATG4 exec...

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Detalles Bibliográficos
Autores principales: Agrotis, Alexander, Pengo, Niccolo, Burden, Jemima J., Ketteler, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526816/
https://www.ncbi.nlm.nih.gov/pubmed/30661429
http://dx.doi.org/10.1080/15548627.2019.1569925