The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis

Macroautophagy/autophagy delivers damaged proteins and organelles to lysosomes for degradation, and plays important roles in maintaining tissue homeostasis by reducing tissue damage. The translocation of LC3 to the limiting membrane of the phagophore, the precursor to the autophagosome, during autop...

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Detalles Bibliográficos
Autores principales: Rai, Shashank, Arasteh, Maryam, Jefferson, Matthew, Pearson, Timothy, Wang, Yingxue, Zhang, Weijiao, Bicsak, Bertalan, Divekar, Devina, Powell, Penny P., Naumann, Ronald, Beraza, Naiara, Carding, Simon R., Florey, Oliver, Mayer, Ulrike, Wileman, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875/
https://www.ncbi.nlm.nih.gov/pubmed/30403914
http://dx.doi.org/10.1080/15548627.2018.1534507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875/
https://www.ncbi.nlm.nih.gov/pubmed/30403914
http://dx.doi.org/10.1080/15548627.2018.1534507

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