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Large-Scale Comparative Analysis of Codon Models Accounting for Protein and Nucleotide Selection

There are numerous sources of variation in the rate of synonymous substitutions inside genes, such as direct selection on the nucleotide sequence, or mutation rate variation. Yet scans for positive selection rely on codon models which incorporate an assumption of effectively neutral synonymous subst...

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Detalles Bibliográficos
Autores principales: Davydov, Iakov I, Salamin, Nicolas, Robinson-Rechavi, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526913/
https://www.ncbi.nlm.nih.gov/pubmed/30847475
http://dx.doi.org/10.1093/molbev/msz048