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Impact of CXCR4 and CXCR7 knockout by CRISPR/Cas9 on the function of triple-negative breast cancer cells

BACKGROUND: Breast cancer is one of the most common malignancies threatening women’s health. Triple-negative breast cancer (TNBC) is a special type of breast cancer with high invasion and metastasis. CXCL12 and its receptors CXCR4 and CXCR7 play a crucial role in the progress of breast cancer. The a...

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Detalles Bibliográficos
Autores principales: Yang, Meng, Zeng, Chen, Li, Peiting, Qian, Liyuan, Ding, Boni, Huang, Lihua, Li, Gang, Jiang, Han, Gong, Ni, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527053/
https://www.ncbi.nlm.nih.gov/pubmed/31190884
http://dx.doi.org/10.2147/OTT.S195661