Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2)

The transport and ion-coupling mechanisms of ZIP transporters remain largely uncharacterized. Previous work in our laboratory has revealed that the solute carrier family 39 member A2 (SLC39A2/ZIP2) increases its substrate transport rate in the presence of extracellular H(+). Here, we used a combinat...

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Detalles Bibliográficos
Autores principales: Gyimesi, Gergely, Albano, Giuseppe, Fuster, Daniel G., Hediger, Matthias A., Pujol-Giménez, Jonai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Membrane Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527156/
https://www.ncbi.nlm.nih.gov/pubmed/30914478
http://dx.doi.org/10.1074/jbc.RA118.006113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527156/
https://www.ncbi.nlm.nih.gov/pubmed/30914478
http://dx.doi.org/10.1074/jbc.RA118.006113

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