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Biochemical characterization of the Lassa virus L protein

The L protein of arena- and bunyaviruses is structurally and functionally related to the orthomyxovirus polymerase complex. It plays a central role in the viral life cycle, as it replicates the virus genome and generates viral mRNA via a cap-snatching mechanism. Here, we aimed to biochemically chara...

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Detalles Bibliográficos
Autores principales: Vogel, Dominik, Rosenthal, Maria, Gogrefe, Nadja, Reindl, Sophia, Günther, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527160/
https://www.ncbi.nlm.nih.gov/pubmed/30926610
http://dx.doi.org/10.1074/jbc.RA118.006973