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A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes

Collagen IV scaffold is a principal component of the basement membrane (BM), a specialized extracellular matrix that is essential for animal multicellularity and tissue evolution. Scaffold assembly begins with the trimerization of α-chains into protomers inside the cell, which then are secreted and...

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Detalles Bibliográficos
Autores principales: Pedchenko, Vadim, Bauer, Ryan, Pokidysheva, Elena N., Al-Shaer, Alaa, Forde, Nancy R., Fidler, Aaron L., Hudson, Billy G., Boudko, Sergei P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527180/
https://www.ncbi.nlm.nih.gov/pubmed/30923125
http://dx.doi.org/10.1074/jbc.RA119.007426