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Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease

Complex systems can fail through different routes, often progressing through a series of (rate-limiting) steps and modified by environmental exposures. The onset of disease, cancer in particular, is no different. Multi-stage models provide a simple but very general mathematical framework for studyin...

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Detalles Bibliográficos
Autor principal: Webster, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527192/
https://www.ncbi.nlm.nih.gov/pubmed/31107895
http://dx.doi.org/10.1371/journal.pone.0216422