Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei

BACKGROUND: Toll-like receptors (TLRs) are sentinel receptors of the innate immune system. TLR4 detects bacterial lipopolysaccharide (LPS) and TLR5 detects bacterial flagellin. A common human nonsense polymorphism, TLR5:c.1174C>T, results in a non-functional TLR5 protein. Individuals carrying thi...

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Detalles Bibliográficos
Autores principales: Dickey, Amy K., Chantratita, Narisara, Tandhavanant, Sarunporn, Ducken, Deirdre, Lovelace-Macon, Lara, Seal, Sudeshna, Robertson, Johanna, Myers, Nicolle D., Schwarz, Sandra, Wurfel, Mark M., Kosamo, Susanna, West, T. Eoin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527242/
https://www.ncbi.nlm.nih.gov/pubmed/31067234
http://dx.doi.org/10.1371/journal.pntd.0007354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527242/
https://www.ncbi.nlm.nih.gov/pubmed/31067234
http://dx.doi.org/10.1371/journal.pntd.0007354

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