Cargando…

Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks

The tumor suppressor protein p53 is activated in response to diverse intrinsic and extrinsic cellular stresses and controls a broad cell-protective gene network. Whether p53:DNA binding and subsequent transcriptional activation differs downstream of these diverse intrinsic and extrinsic activators i...

Descripción completa

Detalles Bibliográficos
Autores principales: Catizone, Allison N., Good, Charly Ryan, Alexander, Katherine A., Berger, Shelley L., Sammons, Morgan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527265/
https://www.ncbi.nlm.nih.gov/pubmed/30966857
http://dx.doi.org/10.1080/15384101.2019.1593643