Oncolytic virus immunotherapy induces immunogenic cell death and overcomes STING deficiency in melanoma

Successful immunotherapy for melanoma depends on the recruitment of effector CD8(+) T cells to the tumor microenvironment. Factors contributing to T cell regulation in melanoma have recently been recognized, including the stimulator of interferon genes (STING). Agents that can activate STING or enha...

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Detalles Bibliográficos
Autores principales: Bommareddy, Praveen K., Zloza, Andrew, Rabkin, Samuel D., Kaufman, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527276/
https://www.ncbi.nlm.nih.gov/pubmed/31143509
http://dx.doi.org/10.1080/2162402X.2019.1591875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527276/
https://www.ncbi.nlm.nih.gov/pubmed/31143509
http://dx.doi.org/10.1080/2162402X.2019.1591875

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