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IRF4-dependent dendritic cells regulate CD8(+) T cell differentiation and memory responses in influenza infection
Acute respiratory disease caused by influenza viruses is imperfectly mitigated by annual vaccination to select strains. Development of vaccines that elicit lung-resident memory CD8(+) T cells (T(RM)) would offer more universal protection to seasonal and emerging pandemic viruses. Understanding how l...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527354/ https://www.ncbi.nlm.nih.gov/pubmed/31089186 http://dx.doi.org/10.1038/s41385-019-0173-1 |