Cargando…

IRF4-dependent dendritic cells regulate CD8(+) T cell differentiation and memory responses in influenza infection

Acute respiratory disease caused by influenza viruses is imperfectly mitigated by annual vaccination to select strains. Development of vaccines that elicit lung-resident memory CD8(+) T cells (T(RM)) would offer more universal protection to seasonal and emerging pandemic viruses. Understanding how l...

Descripción completa

Detalles Bibliográficos
Autores principales: Ainsua-Enrich, Erola, Hatipoglu, Ibrahim, Kadel, Sapana, Turner, Sean, Paul, Jinny, Singh, Simar, Bagavant, Harini, Kovats, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527354/
https://www.ncbi.nlm.nih.gov/pubmed/31089186
http://dx.doi.org/10.1038/s41385-019-0173-1