Vascular smooth muscle cell loss underpins the accelerated atherosclerosis in Hutchinson-Gilford progeria syndrome

Lamin A, a product of the LMNA gene, is an essential nuclear envelope component in most differentiated cells. Mutations in LMNA have been linked to premature aging disorders, including Hutchinson-Gilford progeria syndrome (HGPS). HGPS is caused by progerin, an aberrant form of lamin A that leads to...

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Detalles Bibliográficos
Autores principales: Hamczyk, Magda R., Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527384/
https://www.ncbi.nlm.nih.gov/pubmed/30900948
http://dx.doi.org/10.1080/19491034.2019.1589359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527384/
https://www.ncbi.nlm.nih.gov/pubmed/30900948
http://dx.doi.org/10.1080/19491034.2019.1589359

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