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BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells

BACKGROUND: The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological potential a...

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Detalles Bibliográficos
Autores principales: Machado, Ana Rita Thomazela, Aissa, Alexandre Ferro, Ribeiro, Diego Luis, Ferreira, Rui Seabra, Sampaio, Suely Vilela, Antunes, Lusânia Maria Greggi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527400/
https://www.ncbi.nlm.nih.gov/pubmed/31131003
http://dx.doi.org/10.1590/1678-9199-JVATITD-1476-18